Cholinesterase - Its significance in anaesthetic practice

被引：100

作者：

Davis, L

Britten, JJ

Morgan, M

机构：

[1] ROYAL LONDON HOSP,LONDON E1 1BB,ENGLAND

[2] HAMMERSMITH HOSP,LONDON W12 0HS,ENGLAND

来源：

ANAESTHESIA | 1997年 / 52卷 / 03期

关键词：

enzyme; cholinesterase;

D O I：

10.1111/j.1365-2044.1997.084-az0080.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Plasma cholinesterase is an enzyme which has importance to the anaesthetist primarily for its role in the metabolism of suxamethonium, although other anaesthetic related drugs that this enzyme metabolises are also increasingly important. In this article we review current thoughts on the function, profile and chemistry of plasma cholinesterase. Causes of variations in the activity of the enzyme are described and the basis of genetic variations is explained.

引用

页码：244 / 260

页数：17

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[2]

Alles GA, 1940, J BIOL CHEM, V133, P375

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