Characterization of a cDNA sequence encoding the peroxisome proliferator activated receptor α in the chicken

被引：39

作者：

Diot, C ^{[1
]}

Douaire, M ^{[1
]}

机构：

[1] INRA, ENSAR, Lab Associe Genet Anim, F-35042 Rennes, France

来源：

POULTRY SCIENCE | 1999年 / 78卷 / 08期

关键词：

reverse transcriptase polymerase chain reaction; cDNA cloning; peroxisome proliferator activated receptor alpha; chicken;

D O I：

10.1093/ps/78.8.1198

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Peroxisome proliferator-activated receptors (PPAR) belong to the superfamily of the nuclear hormone receptors that play an important role in lipid homeostasis. A partial complementary deoxyribonucleic acid clone encoding a PPAR alpha from chicken liver was isolated and sequenced. Comparison with human, mouse, rat, and Xenopus PPAR alpha cDNA indicates a high degree of homology, especially at the level of the inferred peptide sequence (greater than 90%). The tissue pattern of expression indicates that PPAR alpha expression in the chicken is similar to that reported in other species, i.e., high expression levels in the liver, heart, and kidney, but also occurs in the lipogenic uropygial gland specific to birds.

引用

页码：1198 / 1202

页数：5

共 25 条

[1]

Belloir B, 1997, EUR J CELL BIOL, V74, P246

[2] Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat [J].

Braissant, O ;

Foufelle, F ;

Scotto, C ;

Dauca, M ;

Wahli, W .

ENDOCRINOLOGY, 1996, 137 (01) :354-366

[3] EVALUATION OF SIMULTANEOUS SELECTION FOR LIVE BODY-WEIGHT AND AGAINST ABDOMINAL FAT IN BROILERS [J].

CAHANER, A ;

NITSAN, Z .

POULTRY SCIENCE, 1985, 64 (07) :1257-1263

[4]

CHOMCZYNSKI P, 1987, ANAL BIOCHEM, V162, P156, DOI 10.1016/0003-2697(87)90021-2

[5] MULTIPLE SEQUENCE ALIGNMENT WITH HIERARCHICAL-CLUSTERING [J].

CORPET, F .

NUCLEIC ACIDS RESEARCH, 1988, 16 (22) :10881-10890

[6] CONTROL OF THE PEROXISOMAL BETA-OXIDATION PATHWAY BY A NOVEL FAMILY OF NUCLEAR HORMONE RECEPTORS [J].

DREYER, C ;

KREY, G ;

KELLER, H ;

GIVEL, F ;

HELFTENBEIN, G ;

WAHLI, W .

CELL, 1992, 68 (05) :879-887

[7] POSITIVE REGULATION OF THE PEROXISOMAL BETA-OXIDATION PATHWAY BY FATTY-ACIDS THROUGH ACTIVATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) [J].

DREYER, C ;

KELLER, H ;

MAHFOUDI, A ;

LAUDET, V ;

KREY, G ;

WAHLI, W .

BIOLOGY OF THE CELL, 1993, 77 (01) :67-76

[8] FATTY-ACIDS ACTIVATE A CHIMERA OF THE CLOFIBRIC ACID-ACTIVATED RECEPTOR AND THE GLUCOCORTICOID RECEPTOR [J].

GOTTLICHER, M ;

WIDMARK, E ;

LI, Q ;

GUSTAFSSON, JA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (10) :4653-4657

[9] WHY ARE YOUNG BROILER-CHICKENS FATTER THAN LAYER-STRAIN CHICKS [J].

GRIFFIN, HD ;

WINDSOR, D ;

GODDARD, C .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-PHYSIOLOGY, 1991, 100 (01) :205-210

[10] ADIPOSE-TISSUE LIPOGENESIS AND FAT DEPOSITION IN LEANER BROILER-CHICKENS [J].

GRIFFIN, HD ;

GUO, KD ;

WINDSOR, D ;

BUTTERWITH, SC .

JOURNAL OF NUTRITION, 1992, 122 (02) :363-368

← 1 2 3 →