Dipeptidyl Peptidase-4, Wound Healing, Scarring, and Fibrosis

被引：20

作者：

Hu, Michael S.

Longaker, Michael T.

机构：

[1] Stanford Univ, Sch Med, Hagey Lab Pediat Regenerat Med, Dept Surg,Div Plast & Reconstruct Surg, Stanford, CA USA

[2] Stanford Univ, Inst Stem Cell Biol & Regenerat Med, Stanford, CA 94305 USA

[3] Univ Hawaii, John A Burns Sch Med, Dept Surg, Honolulu, HI 96822 USA

来源：

PLASTIC AND RECONSTRUCTIVE SURGERY | 2016年 / 138卷 / 05期

关键词：

MOUSE MODEL; INHIBITION; INFLAMMATION; MECHANISMS; DPP-4; DYSFUNCTION; ACTIVATION; PROTECTS; DISEASE; KIDNEY;

D O I：

10.1097/PRS.0000000000002634

中图分类号：

R61 [外科手术学];

学科分类号：

100210 [外科学];

摘要：

Scarring and fibrosis are an enormous public health concern, resulting in excessive morbidity and mortality in addition to countless lost health care dollars. Recent advances in cell and developmental biology promise a better understanding of scarring and fibrosis and may translate to new clinical therapies.

引用

页码：1026 / 1031

页数：6

共 43 条

[1]

Fibroblast activation protein:: a serine protease expressed at the remodeling interface in idiopathic pulmonary flbrosis [J].

Acharya, PS ;

Zukas, A ;

Chandan, V ;

Katzenstein, ALA ;

Puré, E .

HUMAN PATHOLOGY, 2006, 37 (03) :352-360

[2]

β-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse [J].

Atit, Radhika ;

Sgaier, Sema K. ;

Mohamed, Othman A. ;

Taketo, Makoto M. ;

Dufort, Daniel ;

Joyner, Alexandra L. ;

Niswander, Lee ;

Conlon, Ronald A. .

DEVELOPMENTAL BIOLOGY, 2006, 296 (01) :164-176

[3]

Heart Failure as a Comorbidity of Diabetes: Role of Dipeptidyl Peptidase 4 [J].

Bando, Yasuko K. ;

Murohara, Toyoaki .

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 2016, 23 (02) :147-154

[4]

Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment [J].

Barry-Hamilton, Vivian ;

Spangler, Rhyannon ;

Marshall, Derek ;

McCauley, Scott ;

Rodriguez, Hector M. ;

Oyasu, Miho ;

Mikels, Amanda ;

Vaysberg, Maria ;

Ghermazien, Haben ;

Wai, Carol ;

Garcia, Carlos A. ;

Velayo, Arleene C. ;

Jorgensen, Brett ;

Biermann, Donna ;

Tsai, Daniel ;

Green, Jennifer ;

Zaffryar-Eilot, Shelly ;

Holzer, Alison ;

Ogg, Scott ;

Thai, Dung ;

Neufeld, Gera ;

Van Vlasselaer, Peter ;

Smith, Victoria .

NATURE MEDICINE, 2010, 16 (09) :1009-U107

[5]

Liver fibrosis [J].

Bataller, R ;

Brenner, DA .

JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (02) :209-218

[6]

Renal fibrosis: novel insights into mechanisms and therapeutic targets [J].

Boor, Peter ;

Ostendorf, Tammo ;

Floege, Juergen .

NATURE REVIEWS NEPHROLOGY, 2010, 6 (11) :643-656

[7]

Dipeptidyl peptidase inhibition prevents diastolic dysfunction and reduces myocardial fibrosis in a Mouse model of Western diet induced obesity [J].

Bostick, Brian ;

Habibi, Javad ;

Ma, Lixin ;

Aroor, Annayya ;

Rehmer, Nathan ;

Hayden, Melvin R. ;

Sowers, James R. .

METABOLISM-CLINICAL AND EXPERIMENTAL, 2014, 63 (08) :1000-1011

[8]

Effects of DPP-4 Inhibitors on the Heart in a Rat Model of Uremic Cardiomyopathy [J].

Chaykovska, Lyubov ;

von Websky, Karoline ;

Rahnenfuehrer, Jan ;

Alter, Markus ;

Heiden, Susi ;

Fuchs, Holger ;

Runge, Frank ;

Klein, Thomas ;

Hocher, Berthold .

PLOS ONE, 2011, 6 (11)

[9]

DPP-4 Inhibition Attenuates Cardiac Dysfunction and Adverse Remodeling Following Myocardial Infarction in Rats with Experimental Diabetes [J].

Connelly, Kim Alexander ;

Zhang, Yanling ;

Advani, Andrew ;

Advani, Suzanne L. ;

Thai, Kerri ;

Yuen, Darren A. ;

Gilbert, Richard E. .

CARDIOVASCULAR THERAPEUTICS, 2013, 31 (05) :259-267

[10]

Circulating Dipeptidyl Peptidase IV Activity Correlates With Cardiac Dysfunction in Human and Experimental Heart Failure [J].

dos Santos, Leonardo ;

Salles, Thiago A. ;

Arruda-Junior, Daniel F. ;

Campos, Luciene C. G. ;

Pereira, Alexandre C. ;

Barreto, Ana Luiza T. ;

Antonio, Ednei L. ;

Mansur, Alfredo J. ;

Tucci, Paulo J. F. ;

Krieger, Jose E. ;

Girardi, Adriana C. C. .

CIRCULATION-HEART FAILURE, 2013, 6 (05) :1029-1038

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