Anti-Mullerian hormone trend after laparoscopic surgery in women with ovarian endometrioma

被引:45
作者
Litta, Pietro [1 ]
D'Agostino, Giulia [1 ]
Conte, Lorena [1 ]
Saccardi, Carlo [1 ]
Cela, Vito [2 ]
Angioni, Stefano [3 ]
Plebani, Mario [1 ]
机构
[1] Univ Padua, Dept Hlth Woman & Child, I-35128 Padua, Italy
[2] Univ Pisa, Santa Chiara Hosp, Dept Obstet & Gynecol, Pisa, Italy
[3] Univ Cagliari, Dept Surg Sci, Div Obstet & Gynecol, Cagliari, Italy
关键词
Endometrioma; laparoscopy; ovarian reserve; serum AMH; EXCISION; MANAGEMENT;
D O I
10.3109/09513590.2012.758704
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Operative laparoscopy is the gold standard in the treatment of endometriotic ovarian cysts. Excisional surgery is the best technique to prevent recurrences and improve symptoms but it may result in ovarian reserve damage due to the removal of healthy ovarian cortex. The aim of this study was to investigate the extent of the ovarian reserve damage after stripping technique of unilateral endometriomas, by dosing the Anti-Mullerian Hormone (AMH). This prospective study was conducted at the Center of Minimally Invasive Pelvic Surgery of the Department of Health of Woman and Child, University of Padua, from October 2010 to June 2012. Twenty-five women underwent excision of monolateral endometriosis ovarian cyst by stripping without accessing a bipolar coagulation and performing an intracortical suture. The AMH serum levels were estimated in the early proliferative phase of the cycle, before surgery (time 0), 24 h after surgery (time 1), the first menstrual cycle after surgery (time 2) and the third menstrual cycle after surgery (time 3). We found a nonstatistically significant decreases in serum AMH levels after surgical excision of the cysts. Our results suggest that an appropriate surgical technique, without the use of the bipolar coagulation of ovarian border, does not determine a significant reduction of ovarian reserve.
引用
收藏
页码:452 / 454
页数:3
相关论文
共 17 条
[1]   Management of ovarian endometrioma [J].
Alborzi, Saeed ;
Zarei, Afsoon ;
Alborzi, Soroosh ;
Alborzi, Mehrnoosh .
CLINICAL OBSTETRICS AND GYNECOLOGY, 2006, 49 (03) :480-491
[2]  
[Anonymous], 2000, INT J GYNECOL OBSTET, V71, P183
[3]   Rate of severe ovarian damage following surgery for endometriomas [J].
Benaglia, Laura ;
Somigliana, Edgardo ;
Vighi, Valentina ;
Ragni, Guido ;
Vercellini, Paolo ;
Fedele, Luigi .
HUMAN REPRODUCTION, 2010, 25 (03) :678-682
[4]   Ovarian endometriosis: from pathogenesis to surgical treatment [J].
Busacca, M ;
Vignali, M .
CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, 2003, 15 (04) :321-326
[5]   Laparoscopic management of adnexal masses: a gold standard? [J].
Canis, M ;
Rabischong, B ;
Houlle, C ;
Botchorishvili, R ;
Jardon, K ;
Safi, A ;
Wattiez, A ;
Mage, G ;
Pouly, JL ;
Bruhat, MA .
CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, 2002, 14 (04) :423-428
[6]   Impact of laparoscopic cystectomy on ovarian reserve: serial changes of serum anti-Mullerian hormone levels [J].
Chang, Hye Jin ;
Han, Sang Hoon ;
Lee, Jung Ryeol ;
Jee, Byung Chul ;
Lee, Byoung Ick ;
Suh, Chang Suk ;
Kim, Seok Hyun .
FERTILITY AND STERILITY, 2010, 94 (01) :343-349
[7]   Anti-Mullerian hormone inhibits initiation of primordial follicle growth in the mouse ovary [J].
Durlinger, ALL ;
Gruijters, MJG ;
Kramer, P ;
Karels, B ;
Ingraham, HA ;
Nachtigal, MW ;
Uilenbroek, JTJ ;
Grootegoed, JA ;
Themmen, APN .
ENDOCRINOLOGY, 2002, 143 (03) :1076-1084
[8]   Ultrasonographic evaluation and anti-mullerian hormone levels after laparoscopic stripping of unilateral endometriomas [J].
Ercan, Cihangir Mutlu ;
Duru, Namik Kemal ;
Karasahin, Kazim Emre ;
Coksuer, Hakan ;
Dede, Murat ;
Baser, Iskender .
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2011, 158 (02) :280-284
[9]   Antimullerian hormone levels after laparoscopic endometrioma stripping surgery [J].
Ercan, Cihangir Mutlu ;
Sakinci, Mehmet ;
Duru, Namik Kemal ;
Alanbay, Ibrahim ;
Karasahin, Kazim Emre ;
Baser, Iskender .
GYNECOLOGICAL ENDOCRINOLOGY, 2010, 26 (06) :468-472
[10]   Relation between pain symptoms and the anatomic location of deep infiltrating endometriosis [J].
Fauconnier, A ;
Chapron, C ;
Dubuisson, JB ;
Vieira, M ;
Dousset, B ;
Bréart, G .
FERTILITY AND STERILITY, 2002, 78 (04) :719-726