CD40-CD40L interactions in atherosclerosis

被引：78

作者：

Laman, JD ^{[1
]}

deSmet, BJGL ^{[1
]}

Schoneveld, A ^{[1
]}

vanMeurs, M ^{[1
]}

机构：

[1] UNIV UTRECHT HOSP, DEPT CARDIOL, INTERUNIV CARDIOL INST NETHERLANDS, NL-3584 CX UTRECHT, NETHERLANDS

来源：

IMMUNOLOGY TODAY | 1997年 / 18卷 / 06期

关键词：

D O I：

10.1016/S0167-5699(97)80022-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The abundant presence of macrophages and activated T cells in atherosclerotic plaques suggests an active involvement of the immune system in this cardiovascular disease. However, insight into cellular interactions inducing relevant effector functions is still limited. Here, Jon Laman and colleagues propose that local interactions between CD40 and CD40 ligand may induce multiple activities by different cell types contributing to atherosclerosis.

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收藏

页码：272 / 277

页数：6

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