Liver: Single breath-hold dynamic subtraction CT with multi-detector row helical technology - Feasibility study

Fifty-two patients with known or suspected hypervascular malignancy were examined to determine the technical feasibility of performing single-breath-hold dynamic subtraction computed tomography (CT) of the liver with multi-detector row helical CT. The precontrast and hepatic arterial CT scans, which were acquired during the same breath hold, were subtracted. The mean liver-to-muscle contrast ratio on the precontrast, hepatic arterial, and subtracted images was 1.3, 1.4, and 2.3, respectively. In 13 patients with lesions, the subtracted images showed a 2.5-fold increase in mean lesion contrast compared with the hepatic arterial CT scans.