A simple novel method for studying the combined inhibitory effects of ethylurea and N,N-dimethylurea on Jack bean urease

被引：12

作者：

Saboury, AA

MoosaviMovahedi, AA

机构：

[1] UNIV TEHRAN, INST BIOCHEM & BIOPHYS, TEHRAN, IRAN

[2] UNIV TARBIAT MODARES, DEPT CHEM, TEHRAN, IRAN

来源：

JOURNAL OF ENZYME INHIBITION | 1997年 / 11卷 / 03期

关键词：

urease; combined inhibitory effects; graphical method; NICKEL;

D O I：

10.3109/14756369709027652

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The kinetics of the inhibition of jack bean urease in the presence of ethylurea and N,N-dimethylurea was studied at pH = 7.0. Both inhibitors were competitive inhibitors. A simple novel method was used for determining the dissociation constants (K-i) values for the inhibition which were 26 and 28 mM respectively.

引用

页码：217 / 222

页数：6

共 18 条

[1]

[Anonymous], [No title captured]

[2] JACK BEAN UREASE (EC 3.5.1.5) . DEMONSTRATION OF A CARBAMOYL-TRANSFER REACTION AND INHIBITION BY NYDROXAMIC ACIDS [J].