Spectroscopic characterization of selected β-sheet hairpin models

被引：41

作者：

Hilario, J

Kubelka, J

Syud, FA

Gellman, SH

Keiderling, TA

机构：

[1] Univ Illinois, Dept Chem, Chicago, IL 60607 USA

[2] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA

来源：

BIOPOLYMERS | 2002年 / 67卷 / 4-5期

关键词：

spectroscopy; beta-sheet hairpin models; alpha helices; IR spectroscopy; vibrational circular dichroism;

D O I：

10.1002/bip.10094

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The IR and vibrational circular dichroism (VCD) spectra of a model two-stranded beta hairpin are compared to those of a related cyclic two-stranded model, which are both stabilized by (D)Pro-Gly turns. The spectra are compared to ab initio based simulations to support specific assignments of the dominant features and suggest a revised interpretation of the IR and VCD spectra for beta sheet containing proteins. (C) 2002 Wiley Periodicals, Inc.

引用

页码：233 / 236

页数：4

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