Poor penetration of the male genital tract by HIV-1 protease inhibitors

被引：46

作者：

Taylor, S ^{[1
]}

Back, DJ

Workman, J

Drake, SM

White, DJ

Choudhury, B

Cane, PA

Beards, GM

Halifax, K

Pillay, D

机构：

[1] Birmingham Heartlands Hosp, Dept Sexual Med, Birmingham B9 5SS, W Midlands, England

[2] Univ Liverpool, Dept Pharmacol & Therapeut, Liverpool L69 3BX, Merseyside, England

[3] Birmingham Heartlands Hosp, Birmingham PHLS Antiviral Susceptibil Reference U, Birmingham B9 5SS, W Midlands, England

来源：

AIDS | 1999年 / 13卷 / 07期

关键词：

D O I：

10.1097/00002030-199905070-00017

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：859 / 860

页数：2

共 12 条

[1] HIV-1 in semen: an isolated virus reservoir [J].

Byrn, RA ;

Zhang, DZ ;

Eyre, R ;

McGowan, K ;

Kiessling, AA .

LANCET, 1997, 350 (9085) :1141-1141

[2] Quantitation of human immunodeficiency virus type 1 RNA in cell free seminal plasma: Comparison of NASBA(TM) with Amplicor(TM) reverse transcription-PCR amplification and correlation with quantitative culture [J].

Dyer, JR ;

Gilliam, BL ;

Eron, JJ ;

Grosso, L ;

Cohen, MS ;

Fiscus, SA .

JOURNAL OF VIROLOGICAL METHODS, 1996, 60 (02) :161-170

[3] Resistance of HIV-1 to antiretroviral agents in blood and seminal plasma: implications for transmission [J].

Eron, JJ ;

Vernazza, PL ;

Johnston, DM ;

Seillier-Moiseiwitsch, S ;

Alcorn, TM ;

Fiscus, SA ;

Cohen, MS .

AIDS, 1998, 12 (15) :F181-F189

[4] High viral load in semen of human immunodeficiency virus type 1-infected men at all stages of disease and its reduction by therapy with protease and nonnucleoside reverse transcriptase inhibitors [J].

Gupta, P ;

Mellors, J ;

Kingsley, L ;

Riddler, S ;

Singh, MK ;

Schreiber, S ;

Cronin, M ;

Rinaldo, CR .

JOURNAL OF VIROLOGY, 1997, 71 (08) :6271-6275

[5] Sexual transmission of an HIV-1 variant resistant to multiple reverse-transcriptase and protease inhibitors [J].

Hecht, FM ;

Grant, RM ;

Petropoulos, CJ ;

Dillon, B ;

Chesney, MA ;

Tian, H ;

Hellmann, NS ;

Bandrapalli, NI ;

Digilio, L ;

Branson, B ;

Kahn, JO .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (05) :307-311

[6]

MARKOWITZ M, 1995, NEW ENGL J MED, V333, P1534, DOI 10.1056/NEJM199512073332304

[7]

Merry C, 1998, AIDS, V12, P325

[8] Saquinavir pharmacokinetics alone and in combination with nelfinavir in HIV-infected patients [J].

Merry, C ;

Barry, MG ;

Mulcahy, F ;

Halifax, KL ;

Back, DJ .

AIDS, 1997, 11 (15) :F117-F120

[9] Quantification of HIV in semen: Correlation with antiviral treatment and immune status [J].

Vernazza, PL ;

Gilliam, BL ;

Dyer, J ;

Fiscus, SA ;

Eron, JJ ;

Frank, AC ;

Cohen, MS .

AIDS, 1997, 11 (08) :987-993

[10]

Winter AJ, 1998, AIDS, V12, pS67

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