In vitro anti-Helicobacter pylori activity of some flavonoids and their metabolites

被引:109
作者
Bae, EA
Han, MJ
Kim, DH
机构
[1] Kyung Hee Univ, Coll Pharm, Seoul 130701, South Korea
[2] Kyung Hee Univ, Dept Food & Nutr, Seoul 130701, South Korea
关键词
D O I
10.1055/s-2006-960805
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The inhibitory effect of flavonoids and phenolic acids, which could be transformed from flavonoids by human intestinal microflora, on the growth of Helicobacter pylori (HP) was investigated. Ponciretin, hesperetin, naringenin and diosmetin were active against HP. Among them, ponciretin was the most potent and its MIC was 10-20 mu g/ml. However, these active compounds against HP did nearly not inhibit the urease activity of HP.
引用
收藏
页码:442 / 443
页数:2
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