In vitro anti-Helicobacter pylori activity of some flavonoids and their metabolites

被引：109

作者：

Bae, EA

Han, MJ

Kim, DH

机构：

[1] Kyung Hee Univ, Coll Pharm, Seoul 130701, South Korea

[2] Kyung Hee Univ, Dept Food & Nutr, Seoul 130701, South Korea

来源：

PLANTA MEDICA | 1999年 / 65卷 / 05期

关键词：

D O I：

10.1055/s-2006-960805

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The inhibitory effect of flavonoids and phenolic acids, which could be transformed from flavonoids by human intestinal microflora, on the growth of Helicobacter pylori (HP) was investigated. Ponciretin, hesperetin, naringenin and diosmetin were active against HP. Among them, ponciretin was the most potent and its MIC was 10-20 mu g/ml. However, these active compounds against HP did nearly not inhibit the urease activity of HP.

引用

页码：442 / 443

页数：2

共 13 条

[1]

Bae FA, 1998, BIOL PHARM BULL, V21, P990, DOI 10.1248/bpb.21.990

[2]

CORREA P, 1988, CANCER RES, V48, P3554

[3] ESSENTIAL ROLE OF UREASE IN PATHOGENESIS OF GASTRITIS INDUCED BY HELICOBACTER-PYLORI IN GNOTOBIOTIC PIGLETS [J].