Expression pattern of novel chick T-box gene, Tbx20

被引：36

作者：

Iio, A

Koide, M

Hidaka, K

Morisaki, T

机构：

[1] Natl Cardiovasc Ctr, Res Inst, Osaka 5658565, Japan

[2] Tokoname Municipal Hosp, Aichi 4798510, Japan

[3] Osaka Univ, Grad Sch Pharmaceut Sci, Dept Mol Pathophysiol, Osaka 5658565, Japan

来源：

DEVELOPMENT GENES AND EVOLUTION | 2001年 / 211卷 / 11期

关键词：

T-box gene; Tbx20; chick embryo; heart development;

D O I：

10.1007/s00427-001-0187-y

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Little is known about the molecular mechanisms involved with the initial specifications of the cardiac mesoderm. In order to identify potential regulatory factors that play important roles in early heart specification, we attempted to isolate the chick H15-related T-box gene and analyze its expression pattern during early development. The chick Tbx20 gene was found to be highly homologous to human, mouse, and zebrafish hrT/Tbx20. Its expression was initially detected in the posterior lateral mesoderm, after which it expanded to the anterior and was intensively co-expressed with a cardiogenic gene, Nkx2.5, in the anterior lateral mesoderm.

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收藏

页码：559 / 562

页数：4

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