Mutation of tyrosine residues involved in the alkylation half reaction of epoxide hydrolase from Agrobacterium radiobacter AD1 results in improved enantioselectivity

被引：61

作者：

Rink, R

Spelberg, JHL

Pieters, RJ

Kingma, J

Nardini, M

Kellogg, RM

Dijkstra, BW

Janssen, DB

机构：

[1] Univ Groningen, Groningen Biomol Sci & Biotechnol Inst, Dept Biochem, NL-9747 AG Groningen, Netherlands

[2] Univ Groningen, Groningen Biomol Sci & Biotechnol Inst, Dept Organ & Mol Inorgan Chem, NL-9747 AG Groningen, Netherlands

[3] Univ Groningen, Groningen Biomol Sci & Biotechnol Inst, BIOSON Res Inst, NL-9747 AG Groningen, Netherlands

[4] Univ Groningen, Groningen Biomol Sci & Biotechnol Inst, Biophys Chem Lab, NL-9747 AG Groningen, Netherlands

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1999年 / 121卷 / 32期

关键词：

D O I：

10.1021/ja990501o

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：7417 / 7418

页数：2

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