Genetics of Sleep

被引:67
作者
Andretic, Rozi [1 ]
Franken, Paul [2 ]
Tafti, Mehdi [2 ]
机构
[1] Inst Neurosci, San Diego, CA 92121 USA
[2] Univ Lausanne, CIG, CH-1015 Lausanne, Switzerland
基金
瑞士国家科学基金会;
关键词
mouse; Drosophila; circadian; homeostasis; EEG; QTL;
D O I
10.1146/annurev.genet.42.110807.091541
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Molecular and genetic approaches in several species have provided new insights into the mechanisms of rest-activity and sleep-wake regulation. Many of these discoveries are believed to support hypotheses about sleep functions, which nevertheless remain elusive. In this review we discuss the specific contribution of both mammalian and invertebrate models to our understanding of the molecular basis of sleep.
引用
收藏
页码:361 / 388
页数:28
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