Chemoselective activation of aldimine in preference to aldehyde by the combination of BF3•OEt2 and water:: Novel catalyst for the Mannich-type reaction

被引：28

作者：

Akiyama, T ^{[1
]}

Takaya, J ^{[1
]}

Kagoshima, H ^{[1
]}

机构：

[1] Gakushuin Univ, Fac Sci, Dept Chem, Toshima Ku, Tokyo 1718588, Japan

来源：

CHEMISTRY LETTERS | 1999年 / 09期

关键词：

D O I：

10.1246/cl.1999.947

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reported herein are that catalytic amount of conventional Lewis acids activated aldimines in preference to aldehydes, and addition of water to BF3. OEt2 accelerated the Mannich-type reaction significantly to afford p-amino carbonyl compounds in high yields.

引用

页码：947 / 948

页数：2

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