A Killer-Protector System Regulates Both Hybrid Sterility and Segregation Distortion in Rice

被引：284

作者：

Yang, Jiangyi ^{[1
,2
]}

Zhao, Xiaobo ^{[1
,2
]}

Cheng, Ke ^{[1
,2
]}

Du, Hongyi ^{[1
,2
]}

Ouyang, Yidan ^{[1
,2
]}

Chen, Jiongjiong ^{[1
,2
]}

Qiu, Shuqing ^{[1
,2
]}

Huang, Jianyan ^{[1
,2
]}

Jiang, Yunhe ^{[1
,2
]}

Jiang, Liwen ^{[3
]}

Ding, Jihua ^{[1
,2
]}

Wang, Jia ^{[1
,2
]}

Xu, Caiguo ^{[1
,2
]}

Li, Xianghua ^{[1
,2
]}

Zhang, Qifa ^{[1
,2
]}

机构：

[1] Huazhong Agr Univ, Natl Key Lab Crop Genet Improvement, Wuhan 430070, Peoples R China

[2] Huazhong Agr Univ, Natl Ctr Plant Gene Res, Wuhan 430070, Peoples R China

[3] Chinese Univ Hong Kong, Sch Life Sci, Shatin 999077, Hong Kong, Peoples R China

来源：

SCIENCE | 2012年 / 337卷 / 6100期

关键词：

PROGRAMMED CELL-DEATH; INDICA-JAPONICA HYBRIDS; ORYZA-SATIVA L; WIDE-COMPATIBILITY; REPRODUCTIVE BARRIER; S-5; LOCUS; GENE; INCOMPATIBILITY; ARABIDOPSIS; STRESS;

D O I：

10.1126/science.1223702

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Hybrid sterility is a major form of postzygotic reproductive isolation that restricts gene flow between populations. Cultivated rice (Oryza sativa L.) consists of two subspecies, indica and japonica; inter-subspecific hybrids are usually sterile. We show that a killer-protector system at the S5 locus encoded by three tightly linked genes [Open Reading Frame 3 (ORF3) to ORF5] regulates fertility in indica-japonica hybrids. During female sporogenesis, the action of ORF5+ (killer) and ORF4+ (partner) causes endoplasmic reticulum (ER) stress. ORF3+ (protector) prevents ER stress and produces normal gametes, but ORF3- cannot prevent ER stress, resulting in premature programmed cell death and leads to embryo-sac abortion. Preferential transmission of ORF3+ gametes results in segregation distortion in the progeny. These results add to our understanding of differences between indica and japonica rice and may aid in rice genetic improvement.

引用

页码：1336 / 1340

页数：5

共 32 条

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