The eukaryotic linear motif resource ELM: 10 years and counting

被引：229

作者：

Dinkel, Holger ^{[1
]}

Van Roey, Kim ^{[1
]}

Michael, Sushama ^{[1
]}

Davey, Norman E. ^{[2
]}

Weatheritt, Robert J. ^{[3
]}

Born, Diana ^{[4
]}

Speck, Tobias ^{[4
]}

Krueger, Daniel ^{[4
]}

Grebnev, Gleb ^{[5
]}

Kuban, Marta ^{[6
]}

Strumillo, Marta ^{[6
,7
]}

Uyar, Bora ^{[1
,7
]}

Budd, Aidan ^{[1
]}

Altenberg, Brigitte ^{[1
]}

Seiler, Markus ^{[1
]}

Chemes, Lucia B. ^{[8
,9
,10
,11
]}

Glavina, Juliana ^{[10
,11
]}

Sanchez, Ignacio E. ^{[10
,11
]}

Diella, Francesca ^{[1
]}

Gibson, Toby J. ^{[1
]}

机构：

[1] European Mol Biol Lab, D-69117 Heidelberg, Germany

[2] Univ Calif San Francisco, Dept Physiol, San Francisco, CA 94158 USA

[3] MRC, Mol Biol Lab, Struct Studies Div, Cambridge CB2 0QH, England

[4] Heidelberg Univ, D-69117 Heidelberg, Germany

[5] Univ Coll Dublin, Sch Biol & Environm Sci, Dublin 4, Ireland

[6] Maria Sklodowska Curie Mem Canc Ctr, Lab Bioinformat & Biostat, PL-02781 Warsaw, Poland

[7] Inst Oncol, PL-02781 Warsaw, Poland

[8] Consejo Nacl Invest Cient & Tecn, Fdn Inst Leloir, Prot Struct Funct & Engn Lab, RA-1405 Buenos Aires, DF, Argentina

[9] Consejo Nacl Invest Cient & Tecn, Inst Invest Bioquim Buenos Aires, RA-1405 Buenos Aires, DF, Argentina

[10] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Quim Biol, RA-1428 Buenos Aires, DF, Argentina

[11] Univ Buenos Aires, Fac Ciencias Exactas & Nat, IQUIBICEN CONICET, RA-1428 Buenos Aires, DF, Argentina

来源：

NUCLEIC ACIDS RESEARCH | 2014年 / 42卷 / D1期

基金：

英国医学研究理事会;

关键词：

ANAPHASE-PROMOTING COMPLEX/CYCLOSOME; INTRINSICALLY UNSTRUCTURED PROTEINS; KEN-BOX; PREDICTION; BINDING; CDC20; ACM1;

D O I：

10.1093/nar/gkt1047

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

The eukaryotic linear motif (ELM http://elm.eu.org) resource is a hub for collecting, classifying and curating information about short linear motifs (SLiMs). For >10 years, this resource has provided the scientific community with a freely accessible guide to the biology and function of linear motifs. The current version of ELM contains similar to 200 different motif classes with over 2400 experimentally validated instances manually curated from >2000 scientific publications. Furthermore, detailed information about motif-mediated interactions has been annotated and made available in standard exchange formats. Where appropriate, links are provided to resources such as switches.elm.eu.org and KEGG pathways.

引用

页码：D259 / D266

页数：8

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