The relation of "acute and transient psychotic disorder" (ICD-10 F23) to bipolar schizoaffective disorder

The aim of this work is to investigate differences between acute and transient psychotic disorders (ATPD: F23 of ICD-10) and bipolar schizoaffective disorders (BSAD). In a controlled prospective and longitudinal study. the compared all inpatients with ATPD treated at Halle university hospital during a 5-year period with matched controls with BSAD. Sociobiographical data were collected using a semi-structured interview. Follow-up investigations were performed at a mean of 2.2-3.3 years after the index episode or 8.2-16.1 years after the first episode by means of standardized instruments. ATPD differs significantly from BSAD on various relevant levels. Such us gender (more female), age at onset (older), development of the full symptomatology (snore rapid). duration of the symptomatology (shorter). acuteness of onset (more acute), preceding stressful life-events (more frequent) and long-term prognosis (better). It is concluded that ATPD and BSAD are different nosological entities. (C) 2002 Elsevier Science Ltd. All rights reserved.