BRAIN AGEING The cognitive neuroscience of ageing

被引：936

作者：

Grady, Cheryl ^{[1
]}

机构：

[1] Rotman Res Inst Baycrest, Toronto, ON M6A 2E1, Canada

来源：

NATURE REVIEWS NEUROSCIENCE | 2012年 / 13卷 / 07期

基金：

加拿大健康研究院;

关键词：

AGE-RELATED-CHANGES; STATE FUNCTIONAL CONNECTIVITY; STRIATAL DOPAMINE SYNTHESIS; WHITE-MATTER INTEGRITY; MEDIAL TEMPORAL-LOBE; CEREBRAL-BLOOD-FLOW; LONG-TERM-MEMORY; WORKING-MEMORY; DEFAULT-MODE; OLDER-ADULTS;

D O I：

10.1038/nrn3256

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The availability of neuroimaging technology has spurred a marked increase in the human cognitive neuroscience literature, including the study of cognitive ageing. Although there is a growing consensus that the ageing brain retains considerable plasticity of function, currently measured primarily by means of functional MRI, it is less clear how age differences in brain activity relate to cognitive performance. The field is also hampered by the complexity of the ageing process itself and the large number of factors that are influenced by age. In this Review, current trends and unresolved issues in the cognitive neuroscience of ageing are discussed.

引用

页码：491 / 505

页数：15

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