Simultaneous occurrence of right adrenocortical tumor and left adrenal neuroblastoma in an infant with Beckwith-Wiedemann syndrome

被引：17

作者：

Alsultan, Abdulrahman ^{[1
,2
]}

Lovell, Mark A. ^{[2
,4
]}

Hayes, Kari L. ^{[2
,3
]}

Allshouse, Michael J. ^{[5
]}

Garrington, Timothy P. ^{[1
,2
]}

机构：

[1] Univ Colorado Denver, Dept Pediat, Aurora, CO 80045 USA

[2] Childrens Hosp, Aurora, CO 80045 USA

[3] Univ Colorado Denver, Dept Pediat Radiol, Aurora, CO 80045 USA

[4] Univ Colorado Denver, Dept Pathol, Aurora, CO 80045 USA

[5] Childrens Hosp Cent Calif, Dept Surg, Madera, CA USA

来源：

PEDIATRIC BLOOD & CANCER | 2008年 / 51卷 / 05期

关键词：

adrenocortical tumor; Beckwith-Wiedemann syndrome; neuroblastoma;

D O I：

10.1002/pbc.21694

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Children with Beckwith-Wiecicniann syndrome (BWS) have increased risk for development of embryonal tumors. We present the case of an infant with BWS who has hypomethylation of LIT1 gene ill the 11p15.5 chromosomal region and at 6 months of age presented With simultaneous Occurrence of neuroblastoma arising from the left adrenal gland and a right adrenocortical tumor. She underwent surgical resection of both tumors and remains tumor free 18 months after surgery.

引用

页码：695 / 698

页数：4

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