Separation of Nanoparticles in Aqueous Multiphase Systems through Centrifugation

被引：174

作者：

Akbulut, Ozge ^{[1
,2
]}

Mace, Charles R. ^{[1
,2
]}

Martinez, Ramses V. ^{[1
,2
]}

Kumar, Ashok A. ^{[3
]}

Nie, Zhihong ^{[1
,2
]}

Patton, Matthew R. ^{[1
,2
]}

Whitesides, George M. ^{[1
,2
,4
,5
]}

机构：

[1] Harvard Univ, Dept Chem, Cambridge, MA 02138 USA

[2] Harvard Univ, Dept Biol Chem, Cambridge, MA 02138 USA

[3] Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA

[4] Harvard Univ, Wyss Inst Biol Inspired Engn, Cambridge, MA 02138 USA

[5] Harvard Univ, Kavli Inst Bionano Sci & Technol, Cambridge, MA 02138 USA

来源：

NANO LETTERS | 2012年 / 12卷 / 08期

基金：

美国国家科学基金会;

关键词：

Centrifugation; nanoparticles; separation; polymers; multiphase systems; GOLD NANORODS; ASPECT-RATIO; SHAPE SEPARATION; SIZE; GRADIENT; PURIFICATION; ABSORPTION; PARTICLES; MECHANISM;

D O I：

10.1021/nl301452x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This paper demonstrates the use of aqueous multiphase systems (MuPSs) as media for rate-zonal centrifugation to separate nanoparticles of different shapes and sizes. The properties of MuPSs do not change with time or during centrifugation; this stability facilitates sample collection after separation. A three-phase system demonstrates the separation of the reaction products (nanorods, nanospheres, and large particles) of a synthesis of gold nanorods, and enriches the nanorods from 48 to 99% in less than ten minutes using a benchtop centrifuge.

引用

页码：4060 / 4064

页数：5

共 24 条

[21] Separation of Nanoparticles in a Density Gradient: FeCo@C and Gold Nanocrystals [J].

Sun, Xiaoming ;

Tabakman, Scott M. ;

Seo, Won-Seok ;

Zhang, Li ;

Zhang, Guangyu ;

Sherlock, Sarah ;

Bai, Lu ;

Dai, Hongjie .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (05) :939-942

[22] Improved Monodispersity of Plasmonic Nanoantennas via Centrifugal Processing [J].

Tyler, Timothy P. ;

Henry, Anne-Isabelle ;

Van Duyne, Richard P. ;

Hersam, Mark C. .

JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2011, 2 (03) :218-222

[23] Shape separation of nanometer cold particles by size-exclusion chromotography [J].

Wei, GT ;

Liu, FK ;

Wang, CRC .

ANALYTICAL CHEMISTRY, 1999, 71 (11) :2085-2091

[24] Separation of nanorods by density gradient centrifugation [J].

Xiong, Bin ;

Cheng, Jing ;

Qiao, Yanxia ;

Zhou, Rui ;

He, Yan ;

Yeung, Edward S. .

JOURNAL OF CHROMATOGRAPHY A, 2011, 1218 (25) :3823-3829

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