Purine based combinatorial chemistry: Solution phase simultaneous addition of functionalities. Iterative deconvolution by orthogonal protection to a single compound with potent antibacterial activity.

被引:7
作者
Fraser, AS [1 ]
Kawasaki, AM [1 ]
Cook, PD [1 ]
机构
[1] ISIS Pharmaceut, Dept Med Chem, Carlsbad, CA 92008 USA
来源
NUCLEOSIDES & NUCLEOTIDES | 1999年 / 18卷 / 4-5期
关键词
D O I
10.1080/15257779908041654
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:1087 / 1089
页数:3
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    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (15) : 5156 - 5164
  • [2] Solution phase combinatorial chemistry. Discovery of novel polyazapyridinophanes with potent antibacterial activity by a solution phase simultaneous addition of functionalities approach
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    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (16) : 3696 - 3708