Simplified syntheses of complex multifunctional nanomaterials

被引:37
作者
Garanger, Elisabeth
Aikawa, Elena
Reynolds, Fred
Weissleder, Ralph
Josephson, Lee [1 ]
机构
[1] Massachusetts Gen Hosp, Ctr Mol Imaging Res, Charlestown, MA 02129 USA
关键词
D O I
10.1039/b809537j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Multifunctional probes are synthesized in a single step using peptide scaffold-based multifunctional single-attachment-point (MSAP) reagents.
引用
收藏
页码:4792 / 4794
页数:3
相关论文
共 13 条
[1]   INTEGRIN ALPHA(V)BETA(3) ANTAGONISTS PROMOTE TUMOR-REGRESSION BY INDUCING APOPTOSIS OF ANGIOGENIC BLOOD-VESSELS [J].
BROOKS, PC ;
MONTGOMERY, AMP ;
ROSENFELD, M ;
REISFELD, RA ;
HU, TH ;
KLIER, G ;
CHERESH, DA .
CELL, 1994, 79 (07) :1157-1164
[2]   Nanoplatforms for targeted molecular imaging in living subjects [J].
Cai, Weibo ;
Chen, Xiaoyuan .
SMALL, 2007, 3 (11) :1840-1854
[3]   Cancer nanotechnology: Opportunities and challenges [J].
Ferrari, M .
NATURE REVIEWS CANCER, 2005, 5 (03) :161-171
[4]   In vivo cancer targeting and imaging with semiconductor quantum dots [J].
Gao, XH ;
Cui, YY ;
Levenson, RM ;
Chung, LWK ;
Nie, SM .
NATURE BIOTECHNOLOGY, 2004, 22 (08) :969-976
[5]  
Haubner R, 1999, J NUCL MED, V40, P1061
[6]   Directional conjugation of antibodies to nanoparticles for synthesis of multiplexed optical contrast agents with both delivery and targeting moieties [J].
Kumar, S. ;
Aaron, J. ;
Sokolov, K. .
NATURE PROTOCOLS, 2008, 3 (02) :314-320
[7]  
Oliver C, 1999, Methods Mol Biol, V115, P331
[8]   alpha v Integrins as receptors for tumor targeting by circulating ligands [J].
Pasqualini, R ;
Koivunen, E ;
Ruoslahti, E .
NATURE BIOTECHNOLOGY, 1997, 15 (06) :542-546
[9]   Quantum dots and multifunctional nanoparticles: new contrast agents for tumor imaging [J].
Rhyner, Matthew N. ;
Smith, Andrew M. ;
Gao, Xiaohu ;
Mao, Hui ;
Yang, Lily ;
Nie, Shuming .
NANOMEDICINE, 2006, 1 (02) :209-217
[10]   In vivo imaging of tumour angiogenesis in mice with the αvβ3 integrin-targeted tracer 99mTc-RAFT-RGD [J].
Sancey, Lucie ;
Ardisson, Valerie ;
Riou, Laurent M. ;
Ahmadi, Mitra ;
Marti-Batlle, Daniele ;
Boturyn, Didier ;
Dumy, Pascal ;
Fagret, Daniel ;
Ghezzi, Catherine ;
Vuillez, Jean-Philippe .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2007, 34 (12) :2037-2047