How the immune system protects the host from infection

被引：108

作者：

Janeway, CA

机构：

[1] Yale Univ, Sch Med, Immunobiol Sect, New Haven, CT 06520 USA

[2] Howard Hughes Med Inst, New Haven, CT 06520 USA

来源：

MICROBES AND INFECTION | 2001年 / 3卷 / 13期

关键词：

T lymphocytes; B lymphocytes; innate immunity; adaptive immunity; suppressor T cells;

D O I：

10.1016/S1286-4579(01)01477-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The immune system is made up of sets of interacting cells. The first to respond in an cases are the antigen-presenting cells (APCs), which are equipped with receptors for microbial patterns. Engagement of these receptors induces co-stimulatory molecules on the surface of the APCs, and allows it to stimulate potent CD4 T-cell responses, and also CD8 T-cell responses. This in turn leads to B-cell-derived antibody responses. The entire response is controlled by suppressor T cells, as predicted many years ago by Richard Gershon. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

收藏

页码：1167 / 1171

页数：5

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