Fecal Microbiota Transplantation Techniques, Applications, and Issues

被引：93

作者：

Borody, Thomas Julius ^{[1
]}

Campbell, Jordana ^{[1
]}

机构：

[1] Ctr Digest Dis, Five Dock, NSW 2046, Australia

来源：

GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 2012年 / 41卷 / 04期

关键词：

Fecal microbiota transplantation; Clostridium difficile; Ulcerative colitis; Probiotics; Microbiome; Microbiota; CLOSTRIDIUM-DIFFICILE-INFECTION; INFLAMMATORY-BOWEL-DISEASE; AUTISTIC SPECTRUM DISORDERS; GUT MICROBIOTA; CHRONIC CONSTIPATION; ULCERATIVE-COLITIS; RECURRENT; BACTERIOTHERAPY; FLORA; DIARRHEA;

D O I：

10.1016/j.gtc.2012.08.008

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Fecal microbiota transplantation (FMT) has gained widespread recognition in light of the recent Clostridium difficile infection (CDI) epidemic, responsible for almost 110,000 deaths per year. The procedure's success rate has caused experts to reflect on what other conditions may benefit. This article provides an overview of (1) description and history of FMT, (2) FMT publications in CDI, (3) the concept of the gut microbiota as a virtual organ, (4) rationale for FMT use, (5) FMT use in inflammatory bowel disease, (6) emerging FMT applications, (7) how FMT is currently performed, and (8) how FMT may be performed in the future.

引用

页码：781 / +

页数：24

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