Roles and Interactions of Burkholderia pseudomallei BpsIR Quorum-Sensing System Determinants

被引:13
作者
Kiratisin, Pattarachai [1 ]
Sanmee, Sittinee [1 ]
机构
[1] Mahidol Univ, Fac Med, Siriraj Hosp, Dept Microbiol, Bangkok 10700, Thailand
关键词
D O I
10.1128/JB.00739-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The Burkholderia pseudomallei quorum-sensing system (QSS), designated BpsIR, is encoded by five bpsR genes and three bpsI genes. This study investigated the roles and interactions of the QSS determinants in terms of gene regulation and protein interaction. We report two novel findings, that BpsR can function as an activator and a repressor for bpsI expression and that BpsR may form homodimers and heterodimers.
引用
收藏
页码:7291 / 7297
页数:7
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