Prognostic value of neopterin levels in treated patients with hypertension and chest pain but without obstructive coronary artery disease

被引:49
作者
Avanzas, P
Arroyo-Espliguero, R
Cosin-Sales, J
Quiles, J
Zouridakis, E
Kaski, JC
机构
[1] St George Hosp, Sch Med, Dept Cardiol Sci, Coronary Artery Dis Res Unit, London SW17 0RE, England
[2] Hosp Univ, Div Cardiol, Guadalajara, Spain
关键词
D O I
10.1016/j.amjcard.2003.11.035
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We sought to assess the relation between circulating levels of inflammation markers, such a's neopterin and C-reactive protein, and the development of adverse cardiovascular events in patients with hypertension but without obstructive coronary artery disease. We observed that patients who developed adverse events during follow-up had significantly higher neopterin levels compared with patients without events. (C) 2004 by Excerpta Medica, Inc.
引用
收藏
页码:627 / 629
页数:3
相关论文
共 7 条
[1]   Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction [J].
Al Suwaidi, J ;
Hamasaki, S ;
Higano, ST ;
Nishimura, RA ;
Holmes, DR ;
Lerman, A .
CIRCULATION, 2000, 101 (09) :948-954
[2]   Prognostic significance of immune activation after acute coronary syndromes [J].
Auer, J ;
Berent, R ;
Lassnig, E ;
Weber, T ;
Eber, B .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2002, 39 (11) :1878-1878
[3]   UNSTABLE ANGINA - A CLASSIFICATION [J].
BRAUNWALD, E .
CIRCULATION, 1989, 80 (02) :410-414
[4]   Increased serum neopterin: a marker of coronary artery disease activity in women [J].
Garcia-Moll, X ;
Cole, D ;
Zouridakis, E ;
Kaski, JC .
HEART, 2000, 83 (03) :346-350
[5]   Serum neopterin and complex stenosis morphology in patients with unstable angina [J].
Garcia-Moll, X ;
Coccolo, F ;
Cole, D ;
Kaski, JC .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 35 (04) :956-962
[6]  
Gupta S, 1997, LANCET, V349, P1252, DOI 10.1016/S0140-6736(05)62447-6
[7]   IMMUNE-RESPONSE ASSOCIATED PRODUCTION OF NEOPTERIN - RELEASE FROM MACROPHAGES PRIMARILY UNDER CONTROL OF INTERFERON-GAMMA [J].
HUBER, C ;
BATCHELOR, JR ;
FUCHS, D ;
HAUSEN, A ;
LANG, A ;
NIEDERWIESER, D ;
REIBNEGGER, G ;
SWETLY, P ;
TROPPMAIR, J ;
WACHTER, H .
JOURNAL OF EXPERIMENTAL MEDICINE, 1984, 160 (01) :310-316