Favorable outcome of pneumonia due to Panton-Valentine leukocidin-producing Staphylococcus aureus associated with hematogenous origin and absence of flu-like illness

被引：12

作者：

Alonso-Tarrés, C

Villegas, ML

de Gispert, FJ

Cortés-Lletget, MC

Plarromaní, AR

Etienne, J

机构：

[1] Hosp Gen lHospitalet, CSI, Serv Anal Clin Microbiol, Barcelona 08906, Spain

[2] Hosp Gen lHospitalet, CSI, Unitat Resp, Barcelona 08906, Spain

[3] Hosp Gen lHospitalet, CSI, Med Interna Serv, Barcelona 08906, Spain

[4] Hosp Gen lHospitalet, CSI, Serv UCI, Barcelona 08906, Spain

[5] Fac Med Laennec, IFR62, INSERM E0230, Ctr Natl Reference Staphylocoques, F-69372 Lyon, France

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2005年 / 24卷 / 11期

关键词：

D O I：

10.1007/s10096-005-0029-3

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Reported here is what is believed to be the first case of community-acquired pneumonia caused by a Panton-Valentine leukocidin-producing strain of Staphylococcus aureus in Spain. Although lung infections caused by S. aureus strains carrying this powerful leukocidin gene are associated with necrotizing pneumonia and high mortality, the previously healthy 28-year-old male reported here experienced a good clinical course and recovery. It is thought that the hematogenous origin of the infection, the patient's lack of any previous respiratory viral infection and prompt initiation of therapy may explain the satisfactory evolution in this case.

引用

收藏

页码：756 / 759

页数：4

相关论文

共 19 条

[1] Life-threatening hemoptysis in adults with community-acquired pneumonia due to Panton-Valentine leukocidin-secreting Staphylococcus aureus [J].

Boussaud, V ;

Parrot, A ;

Mayaud, C ;

Wislez, M ;

Antoine, M ;

Picard, C ;

Delisle, F ;

Etienne, J ;

Cadranel, J .

INTENSIVE CARE MEDICINE, 2003, 29 (10) :1840-1843

[2]

Couppie P, 1997, ANN DERMATOL VENER, V124, P740

[3]

Couppie P, 1997, ANN DERMATOL VENER, V124, P684

[4] Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes [J].

Francis, JS ;

Doherty, MC ;

Lopatin, U ;

Johnston, CP ;

Sinha, G ;

Ross, T ;

Cai, M ;

Hansel, NN ;

Perl, T ;

Ticehurst, JR ;

Carroll, K ;

Thomas, DL ;

Nuermberger, E ;

Bartlett, JG .

CLINICAL INFECTIOUS DISEASES, 2005, 40 (01) :100-107

[5] Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients [J].

Gillet, Y ;

Issartel, B ;

Vanhems, P ;

Fournet, JC ;

Lina, G ;

Bes, M ;

Vandenesch, F ;

Piémont, Y ;

Brousse, N ;

Floret, D ;

Etienne, J .

LANCET, 2002, 359 (9308) :753-759

[6] Relationships between Staphylococcus aureus genetic background, virulence factors, agr groups (Alleles), and human disease [J].

Jarraud, S ;

Mougel, C ;

Thioulouse, J ;

Lina, G ;

Meugnier, H ;

Forey, F ;

Nesme, X ;

Etienne, J ;

Vandenesch, F .

INFECTION AND IMMUNITY, 2002, 70 (02) :631-641

[7] Breast milk transmission of a Panton-Valentine leukocidin-producing Staphylococcus aureus strain causing infantile pneumonia [J].

Le Thomas, I ;

Mariani-Kurkdjian, P ;

Collignon, A ;

Gravet, A ;

Clermont, O ;

Brahimi, N ;

Gaudelus, J ;

Aujard, Y ;

Navarro, J ;

Beaufils, F ;

Bingen, E .

JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (02) :728-729

[8] Community-acquired methicillin-resistant Staphylococcus aureus isolated in Switzerland contains the Panton-Valentine leukocidin or exfoliative toxin genes [J].

Liassine, N ;

Auckenthaler, R ;

Descombes, MC ;

Bes, M ;

Vandenesch, F ;

Etienne, J .

JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (02) :825-828

[9] Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia [J].

Lina, G ;

Piémont, Y ;

Godail-Gamot, F ;

Bes, M ;

Peter, MO ;

Gauduchon, V ;

Vandenesch, F ;

Etienne, J .

CLINICAL INFECTIOUS DISEASES, 1999, 29 (05) :1128-1132

[10] Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles [J].

Miller, LG ;

Perdreau-Remington, F ;

Rieg, G ;

Mehdi, S ;

Perlroth, J ;

Bayer, AS ;

Tang, AW ;

Phung, TO ;

Spellberg, B .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (14) :1445-1453