Fetal or infant death in twin pregnancy: neurodevelopmental consequence for the survivor

被引:37
作者
Glinianaia, SV
Pharoah, POD
Wright, C
Rankin, JM
机构
[1] Newcastle Univ, Sch Med, Sch Hlth Sci, Dept Epidemiol & Publ Hlth, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
[2] Newcastle Univ, Reg Matern Survey Off, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
[3] Dept Pathol, Newcastle Upon Tyne NE2 4AA, Tyne & Wear, England
[4] Reg Matern Survey Off, Newcastle Upon Tyne NE2 4AA, Tyne & Wear, England
来源
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION | 2002年 / 86卷 / 01期
关键词
D O I
10.1136/fn.86.1.F9
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Aim: To determine the neurodevelopmental morbidity in the surviving twin after fetal or infant death of the co-twin. Methods: Twin pregnancies with an antepartum or infant death delivered between 1981 and 1992 were identified from the Northern Perinatal Mortality Survey. Information on the neurodevelopmental morbidity of infant survivors of a deceased co-twin was obtained by a questionnaire sent to the community paediatrician or general practitioner. Results: A total of 1 1 1 children who survived infancy after the fetal death of the co-twin (group 1) and 142 from liveborn twin pairs in which one twin died in infancy (group 2) were traced. Responses were received from 97 (87%) and 130 (92%) respectively. In group 1, the cerebral palsy prevalence was 93 pairs (8/70) with a prevalence of 1 14 (95% Cl 51 to 213) compared with 45 (95% Cl I to 228) per 1000 infant survivors in unlike-sex pairs (1/22). The overall morbidity (including developmental delay) was 175 (95% Cl 106 to 266) per 1000. In group 2, the cerebral palsy prevalence was 154 (95% Cl 84 to 223) per 1000 infant survivors in like-sex (16/104) and 77 (95% Cl 9 to 25 1) in unlike-sex (2/26) survivors; the overall prevalence of neurodevelopmental morbidity was 246 (95% Cl 172 to 320) per 1000. Conclusions: The risk of cerebral palsy is increased in the surviving twin after a fetal or infant co-twin death compared with the general twin population. Like-sex twins are at greater risk than unlike-sex. The probable cause, in addition to the consequence associated with monochorionicity.
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页码:F9 / F15
页数:7
相关论文
共 42 条
  • [1] CENTRAL-NERVOUS-SYSTEM DAMAGE AND OTHER ANOMALIES IN SURVIVING FETUS FOLLOWING 2ND TRIMESTER ANTENATAL DEATH OF COTWIN - REPORT OF 4 CASES AND LITERATURE-REVIEW
    ANDERSON, RL
    GOLBUS, MS
    CURRY, CJR
    CALLEN, PW
    HASTRUP, WH
    [J]. PRENATAL DIAGNOSIS, 1990, 10 (08) : 513 - 518
  • [2] [Anonymous], 2000, CLIN DEV MED
  • [3] Maternal and neonatal outcome of twin pregnancies complicated by single fetal death
    Axt, R
    Mink, D
    Hendrik, J
    Ertan, K
    von Blohn, M
    Schmidt, W
    [J]. JOURNAL OF PERINATAL MEDICINE, 1999, 27 (03) : 221 - 227
  • [4] Intrapartum risk factors for newborn encephalopathy: the Western Australian case-control study
    Badawi, N
    Kurinczuk, JJ
    Keogh, JM
    Alessandri, LM
    O'Sullivan, F
    Burton, PR
    Pemberton, PJ
    Stanley, FJ
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 1998, 317 (7172): : 1554 - 1558
  • [5] Outcome of twin pregnancies complicated by single intrauterine death in relation to vascular anatomy of the monochorionic placenta
    Bajoria, R
    Wee, LY
    Anwar, S
    Ward, S
    [J]. HUMAN REPRODUCTION, 1999, 14 (08) : 2124 - 2130
  • [6] Only a minor part of cerebral palsy cases begin in labour - But still room for controversial childbirth issues in court
    Bakketeig, LS
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 1999, 319 (7216): : 1016 - 1017
  • [7] BAX M C, 1964, Dev Med Child Neurol, V6, P295
  • [8] ANTENATAL ORIGIN OF NEUROLOGIC DAMAGE IN NEWBORN-INFANTS .2. MULTIPLE GESTATIONS
    BEJAR, R
    VIGLIOCCO, G
    GRAMAJO, H
    SOLANA, C
    BENIRSCHKE, K
    BERRY, C
    COEN, R
    RESNIK, R
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1990, 162 (05) : 1230 - 1236
  • [9] BENIRSCHKE K, 1993, SEMIN DIAGN PATHOL, V10, P222
  • [10] SINGLE FETAL DEMISE IN TWIN GESTATION
    BURKE, MS
    [J]. CLINICAL OBSTETRICS AND GYNECOLOGY, 1990, 33 (01) : 69 - 78