Delayed-type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: Confirmation by in vivo and in vitro tests

被引：55

作者：

Bircher, AJ ^{[1
]}

Messmer, SL ^{[1
]}

Surber, C ^{[1
]}

Rufli, T ^{[1
]}

机构：

[1] UNIV BASEL HOSP, DEPT DERMATOL, ALLERGY UNIT, CH-4031 BASEL, SWITZERLAND

来源：

CONTACT DERMATITIS | 1996年 / 34卷 / 06期

关键词：

delayed-type hypersensitivity; aminoacylamide local anesthetics; lidocaine; articaine; cross-reactivity; patch tests; intradermal tests; subcutaneous challenge; lymphocyte transformation test;

D O I：

10.1111/j.1600-0536.1996.tb02238.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

A 43-year-old woman suffered from recurrent localized swellings and an eczematous dermatitis starting 1 day after an injection of lidocaine. Intradermal, patch and lymphocyte transformation tests revealed sensitization to lidocaine and cross-reactivity to the other aminoacylamide local anesthetics bupivacaine, mepivacaine and prilocaine, but not to articaine. Contact allergy to the ester local anesthetics benzocaine, procaine and tetracaine, the quinoline or aminoalkylamide cinchocaine, and the preservatives methylparaben and metabisulfite, was excluded. A subcutaneous challenge with articaine was well tolerated. (C) Munksgaard, 1996.

引用

页码：387 / 389

页数：3

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