A neural correlate of oculomotor sequences in supplementary eye field

被引:76
作者
Lu, XF [1 ]
Matsuzawa, M [1 ]
Hikosaka, O [1 ]
机构
[1] Juntendo Univ, Sch Med, Dept Physiol, Tokyo 1138421, Japan
基金
日本学术振兴会;
关键词
D O I
10.1016/S0896-6273(02)00657-8
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Complex learned motor sequences can be composed of a combination of a small number of elementary actions. To investigate how the brain represents such sequences, we devised an oculomotor sequence task in which the monkey had to choose the target solely by the sequential context, not by the current stimulus combination. We found that many neurons in the supplementary eye field (SEF) became active with a specific target direction (D neuron) or a specific target/distractor combination (C neuron). Furthermore, such activity was often selective for one among several sequences that included the combination (S neuron). These results suggest that the SEF contributes to the generation of saccades in many learned sequences.
引用
收藏
页码:317 / 325
页数:9
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