A general framework for neural network models on censored survival data

被引:47
作者
Biganzoli, E
Boracchi, P
Marubini, E
机构
[1] Ist Nazl Studio & Cura Tumori, Unita Operat Stat Med & Biometria, I-20133 Milan, Italy
[2] Univ Milan, Ist Stat Med & Biometria, I-20133 Milan, Italy
关键词
outcome prediction; survival data; feed forward artificial neural networks;
D O I
10.1016/S0893-6080(01)00131-9
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
Flexible parametric techniques for regression analysis, such as those based on feed forward artificial neural networks (FFANNs), can be useful for the statistical analysis of censored time data. These techniques are of particular interest for the study of the outcome dependence from several variables measured on a continuous scale, since they allow for the detection of complex non-linear and non-additive effects. Few efforts have been made until now to account for censored times in FFANNs. In the attempt to fill this gap, specific error functions and data representation will be introduced for multilayer perceptron and radial basis function extensions of generalized linear models for survival data. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:209 / 218
页数:10
相关论文
共 28 条
[1]  
Aitkin M., 1989, STAT MODELLING GLIM
[2]  
[Anonymous], 1969, DISTRIBUTIONS STAT D
[3]  
[Anonymous], 1983, APPL STAT
[4]   APPLICATION OF ARTIFICIAL NEURAL NETWORKS TO CLINICAL MEDICINE [J].
BAXT, WG .
LANCET, 1995, 346 (8983) :1135-1138
[5]  
Biganzoli E, 1998, STAT MED, V17, P1169, DOI 10.1002/(SICI)1097-0258(19980530)17:10<1169::AID-SIM796>3.3.CO
[6]  
2-4
[7]  
BIGANZOLI E, 1999, MODELLING SIMULATION, V2, P167
[8]  
Bishop C. M., 1995, NEURAL NETWORKS PATT
[9]  
BORACCHI P, 2001, IN PRESS METRON
[10]   Time-dependent relevance of steroid receptors in breast cancer [J].
Coradini, D ;
Daidone, MG ;
Boracchi, P ;
Biganzoli, E ;
Oriana, S ;
Bresciani, G ;
Pellizzaro, C ;
Tomasic, G ;
Di Fronzo, G ;
Marubini, E .
JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (14) :2702-2709