Economic evaluation of sacral nerve stimulation for faecal incontinence

被引:55
作者
Dudding, T. C. [1 ]
Lee, E. Meng [2 ]
Faiz, O. [1 ]
Pares, D. [1 ]
Vaizey, C. J. [1 ]
McGuire, A. [2 ]
Kamm, M. A. [1 ]
机构
[1] St Marks Hosp, Dept Physiol, Harrow HA1 3UJ, Middx, England
[2] London Sch Econ, London WC2A 2AE, England
关键词
D O I
10.1002/bjs.6237
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background; Sacral nerve stimulation (SNS) is an established treatment for faecal incontinence in patients who have failed conservative management. This study established the cost-effectiveness of treating patients with SNS compared with non-surgical treatment. Methods: A decision analysis model was performed. Data from 70 patients were obtained from medical records, bowel habit diaries and Short Form 36 quality of life questionnaires. Direct medical and non-medical costs were ascertained using the 2005/2006 national tariff, national statistics, and medication, pad and device costs. Indirect non-medical costs were also estimated. Results: Incontinence episodes were reduced from a median of 12 per fortnight at baseline to one per fortnight with SNS. Based on direct medical and non-medical costs, the incremental cost-effectiveness ratio (ICER) for SNS was 25 pound 070 per QALY gained. It cost 1038 pound more per year to treat patients with SNS for a median reduction of 286 incontinence episodes, equating to 3.63 pound per episode reduced. When indirect non-medical costs were included the ICER was reduced to 12 pound 959 per QALY gained. Conclusion: The ICER of 25 pound 070 is within the 30 pound 000 per QALY threshold recommended by the National Institute for Health and Clinical Excellence as an effective use of National Health Service resources with proper justification.
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页码:1155 / 1163
页数:9
相关论文
共 34 条
[1]  
[Anonymous], 2006, MEDTRONIC INSTRUCTIO
[2]   Measuring fecal incontinence [J].
Baxter, NN ;
Rothenberger, DA ;
Lowry, AC .
DISEASES OF THE COLON & RECTUM, 2003, 46 (12) :1591-1605
[3]   Does incontinence severity correlate with quality of life? Prospective analysis of 502 consecutive patients [J].
Bordeianou, L. ;
Rockwood, T. ;
Baxter, N. ;
Lowry, A. ;
Mellgren, A. ;
Parker, S. .
COLORECTAL DISEASE, 2008, 10 (03) :273-279
[4]   The estimation of a preference-based measure of health from the SF-36 [J].
Brazier, J ;
Roberts, J ;
Deverill, M .
JOURNAL OF HEALTH ECONOMICS, 2002, 21 (02) :271-292
[5]   Deriving a preference-based single index from the UK SF-36 Health Survey [J].
Brazier, J ;
Usherwood, T ;
Harper, R ;
Thomas, K .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 1998, 51 (11) :1115-1128
[6]  
*BRIT MED ASS ROYA, 2005, BRIT NAT FORM
[7]   Antenatal prediction of postpartum urinary and fecal incontinence [J].
Chaliha, C ;
Kalia, V ;
Stanton, SL ;
Monga, A ;
Sultan, AH .
OBSTETRICS AND GYNECOLOGY, 1999, 94 (05) :689-694
[8]   Sacral nerve stimulation can be successful in patients with ultrasound evidence of external anal sphincter disruption [J].
Conaghan, P ;
Farouk, R .
DISEASES OF THE COLON & RECTUM, 2005, 48 (08) :1610-1614
[9]  
*DEP HLTH UK, NAT TAR 2005 2006
[10]   Costs of outpatients with fecal incontinence [J].
Deutekom, M ;
Dobben, AC ;
Dijkgraaf, MGW ;
Terra, MP ;
Stoker, J ;
Bossuyt, PMM .
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2005, 40 (05) :552-558