Quercetin, but not its glycosides, is absorbed from the rat stomach

被引：170

作者：

Crespy, V ^{[1
]}

Morand, C ^{[1
]}

Besson, C ^{[1
]}

Manach, C ^{[1
]}

Demigne, C ^{[1
]}

Remesy, C ^{[1
]}

机构：

[1] INRA, Lab Malad Metab & Micronutriments, F-63122 St Genes Champanelle, France

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2002年 / 50卷 / 03期

关键词：

quercetin; flavonoid glucosides; stomach; absorption; rat;

D O I：

10.1021/jf010919h

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Absorption and metabolism of quercetin, isoquercitrin (quercetin 3-O-glucose), and rutin (quercetin 3-O-glucose-rhamnose) were investigated in rats after in situ gastric administration (15 mumol/L) for 30 min. At the end of the experiment, 38% of the initial dose of quercetin had disappeared. Quercetin was rapidly absorbed by the stomach, and was recovered in the bile 20 min after infusion (4.07 +/- 0.10 mumol/L). The administration of rutin and isoquercitrin indicated that these glycosides were not hydrolyzed nor absorbed by this tissue. In conclusion, when flavonols are present in the diet as aglycons, they could be partly absorbed in the stomach, in contrast to their glycosidic forms which are not absorbed.

引用

页码：618 / 621

页数：4

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