Intramolecular migration of [Pt(dien)](2+) (dien = 1,5-diamino-3-azapentane) from sulfur to imidazole-N-1 in histidylmethionine (his-metH)

被引：29

作者：

Frohling, CDW ^{[1
]}

Sheldrick, WS ^{[1
]}

机构：

[1] RUHR UNIV BOCHUM,LEHRSTUHL ANALYT CHEM,D-44780 BOCHUM,GERMANY

来源：

CHEMICAL COMMUNICATIONS | 1997年 / 18期

关键词：

D O I：

10.1039/a702904g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

HPLC and NMR investigations of the kinetics of competitive binding by neighbouring side chains in his-metH demonstrate that at pH > 6 initial S coordination is followed by slow isomerization to an imidazole-N-1 bound complex through a dinuclear intermediate [{Pt(dien)}(2)(his-metH-1 kappa N-1:2 kappa S)]4(+).

引用

页码：1737 / 1738

页数：2

共 12 条

[1] LINKAGE ISOMERISM IN SQUARE-PLANAR COMPLEXES OF PLATINUM AND PALLADIUM WITH HISTIDINE AND DERIVATIVES [J].

APPLETON, TG ;

PESCH, FJ ;

WIENKEN, M ;

MENZER, S ;

LIPPERT, B .

INORGANIC CHEMISTRY, 1992, 31 (21) :4410-4419

[2] S,O-CHELATION VERSUS S,N-CHELATION IN THE REACTIONS OF THE CIS-DIAMMINEDIAQUAPLATINUM(II) CATION WITH METHIONINE AND S-METHYLCYSTEINE [J].

APPLETON, TG ;

CONNOR, JW ;

HALL, JR .

INORGANIC CHEMISTRY, 1988, 27 (01) :130-137

[3] NMR-STUDY OF THE REACTIONS OF THE CIS-DIAMMINEDIAQUAPLATINUM(II) CATION WITH GLUTATHIONE AND AMINO-ACIDS CONTAINING A THIOL-GROUP [J].

APPLETON, TG ;

CONNOR, JW ;

HALL, JR ;

PRENZLER, PD .

INORGANIC CHEMISTRY, 1989, 28 (11) :2030-2037

[4] L-METHIONINE INCREASES THE RATE OF REACTION OF 5'-GUANOSINE MONOPHOSPHATE WITH THE ANTICANCER DRUG CISPLATIN - MIXED-LIGAND ADDUCTS AND REVERSIBLE METHIONINE BINDING [J].

BARNHAM, KJ ;

DJURAN, MI ;

MURDOCH, PD ;

RANFORD, JD ;

SADLER, PJ .

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1995, (22) :3721-3726

[5] INTERMOLECULAR DISPLACEMENT OF S-BOUND L-METHIONINE ON PLATINUM(II) BY GUANOSINE 5'-MONOPHOSPHATE - IMPLICATIONS FOR THE MECHANISM OF ACTION OF ANTICANCER DRUGS [J].

BARNHAM, KJ ;

DJURAN, MI ;

MURDOCH, PD ;

SADLER, PJ .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1994, (06) :721-722

[6] INTERACTIONS OF PLATINUM AMINE COMPOUNDS WITH SULFUR-CONTAINING BIOMOLECULES AND DNA FRAGMENTS [J].

LEMPERS, ELM ;

REEDIJK, J .

ADVANCES IN INORGANIC CHEMISTRY, 1991, 37 :175-217

[7]

PRESTAYKO AW, 1980, CISPLATIN CURRENT ST, P2

[8] Reversed-phase liquid chromatographic separation of platinum(II) complexes of methionine- and histidine-containing peptides using perfluorinated carboxylic acids as ion-pairing reagents [J].

Siebert, AFM ;

Frohling, CDW ;

Sheldrick, WS .

JOURNAL OF CHROMATOGRAPHY A, 1997, 761 (1-2) :115-127

[9] pH-Dependent competition between N,S and N,N' chelation in the reaction of [Pt(en)(H2O)(2)](2+) (en=H2NCH2CH2NH2) with methionine-containing di- and tri-peptides [J].

Siebert, AFM ;

Sheldrick, WS .

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1997, (03) :385-393

[10]

VANBOOM SSG, 1995, THESIS U LEIDEN

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