Intestinal microbiota development in the premature neonate: establishment of a lasting commensal relationship?

被引：57

作者：

Mshvildadze, Maka ^{[2
]}

Neu, Josef ^{[1
]}

Mai, Volker ^{[3
]}

机构：

[1] Univ Florida, Dept Pediat, Gainesville, FL 32610 USA

[2] Georgian Inst Perinatal Med, Tbilisi, Georgia

[3] Univ Florida, Microbiol & Cell Sci & Emerging Pathogens Inst, Gainesville, FL 32610 USA

来源：

NUTRITION REVIEWS | 2008年 / 66卷 / 11期

关键词：

intestine; microbiome; microbiota; necrotizing enterocolitis; premature infant;

D O I：

10.1111/j.1753-4887.2008.00119.x

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

The gastrointestinal tract of premature infants is a highly fragile organ due to numerous developmental immaturities. Exposure to luminal microbes in the first several weeks of these infants' lives may play a significant role in the development of short-term disease and may have profound effects on long-term health. New non-culture-based techniques are providing exciting new insights into how the intestinal microbiota of premature infants develops and relates to health. A brief summary of recent research in this area is presented, which may be adapted to nutritional strategies for disease prevention. (C) 2008 International Life Sciences Institute

引用

页码：658 / 663

页数：6

共 44 条

[1] DEVELOPMENT OF THE FECAL ANAEROBIC MICROFLORA AFTER CESAREAN-SECTION AND TREATMENT WITH ANTIBIOTICS IN NEWBORN-INFANTS [J].