A formylating agent by dehydration of the natural product DIMBOA

被引：6

作者：

Hofmann, A ^{[1
]}

Sicker, D ^{[1
]}

机构：

[1] Univ Leipzig, Inst Organ Chem, D-04103 Leipzig, Germany

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 08期

关键词：

D O I：

10.1021/np980515s

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The natural aglucone 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one (DIMBOA, 1) of maize underwent spontaneous dehydration and rearrangement to form 3-formyl-6-methoxybenzoxazolin-2(3H)-one (FMBOA, 2) on reaction with N-ethoxycarbonyl-trichloroacetaldimine. Compound 2 was proven to be a reactive formyl donor toward N-, 0-, and S-nucleophiles, which may be important in case 2 is formed under biological conditions.

引用

页码：1151 / 1153

页数：3

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