Non-fouling oligo(ethylene glycol)-functionalized polymer brushes synthesized by surface-initiated atom transfer radical polymerization

被引：613

作者：

Ma, HW ^{[1
]}

Hyun, JH ^{[1
]}

Stiller, P ^{[1
]}

Chilkoti, A ^{[1
]}

机构：

[1] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA

来源：

ADVANCED MATERIALS | 2004年 / 16卷 / 04期

关键词：

D O I：

10.1002/adma.200305830

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The in-situ synthesis of oligo(ethylene glycol) -functionalized polymer brushes from a self-assembled monolayer of an alkanethiol on gold that presents a tethered initiator by surface-initiated atom transfer radical polymerization is reported. These polymer brushes exhibit no detectable adsorption of proteins, and are cell-resistant for up to a month under typical cell culture conditions. The synthesis method is compatible with a range of patterning techniques from the nano- to the microscale, and enables the patterning of cells in a biologically relevant milieu over extended periods of time. Images of the brushes are shown on the inside front cover.

引用

页码：338 / +

页数：5

共 49 条

[1] DEFINED SUB-GENOMIC FRAGMENT OF INVITRO SYNTHESIZED MOLONEY SARCOMA-VIRUS DNA CAN INDUCE CELL TRANSFORMATION UPON TRANSFECTION [J].