Interaction between posaconazole and caspofungin in concomitant treatment of mice with systemic Aspergillus infection

被引：22

作者：

Cacciapuoti, A ^{[1
]}

Halpern, J ^{[1
]}

Mendrick, C ^{[1
]}

Norris, C ^{[1
]}

Patel, R ^{[1
]}

Loebenberg, D ^{[1
]}

机构：

[1] Schering Plough Res Inst, Kenilworth, NJ 07033 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 07期

关键词：

D O I：

10.1128/AAC.00829-05

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The interaction of posaconazole and caspofungin was evaluated in concomitant treatment of Aspergillus fimigatus (two strains) or A. flavus (one strain) systemic infections in immunocompetent mice. Survival curves for mice treated with the combinations were compared statistically with those for mice treated with the component monotherapies. No antagonism was observed.

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收藏

页码：2587 / 2590

页数：4

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