Zoledronic acid in treatment of bone lesions by Langerhans cell histiocytosis

被引：32

作者：

Montella, Liliana ^{[1
]}

Merola, Carmela

Merola, Geraldina ^{[2
]}

Petillo, Luigi ^{[2
]}

Palmieri, Giovannella ^{[2
]}

机构：

[1] S Giovanni Dio Hosp, Med Oncol Unit, Naples, Italy

[2] Univ Naples Federico 2, Mol & Clin Endocrinol & Oncol Dept, Naples, Italy

来源：

JOURNAL OF BONE AND MINERAL METABOLISM | 2009年 / 27卷 / 01期

关键词：

Langerhans cell histiocytosis; Bone lesions; Zoledronic acid; BISPHOSPHONATES; PAMIDRONATE;

D O I：

10.1007/s00774-008-0001-2

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Langerhans cell histiocytosis (LCH) is a rare disease, probably an atypical myeloproliferative syndrome, with variable clinical presentation and behavior. In this report, we focus on bone involvement by LCH and treatment with zoledronic acid in six patients as they progressed after chemotherapy and radiotherapy. Zoledronic acid appeared safe and produced significant relief in pain.

引用

页码：110 / 113

页数：4

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