Hydrodynamic radius of circular DNA is larger than that of linear DNA

被引：32

作者：

Araki, S

Nakai, T

Hizume, K

Takeyasu, K

Yoshikawa, K ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Sci, Dept Phys, Kyoto 6068502, Japan

[2] Kyoto Univ, Grad Sch Biostudies, Lab Plasma Membrane & Nucl Signaling, Kyoto 6068502, Japan

来源：

CHEMICAL PHYSICS LETTERS | 2006年 / 418卷 / 1-3期

基金：

日本学术振兴会;

关键词：

D O I：

10.1016/j.cplett.2005.10.115

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

it is generally accepted that linear polymers are larger, such as with regard to the end-to-end distance and gyration radius, than the corresponding circular polymers. We measured the Brownian motion of individual linear and circular 106-kbp DNA molecules using fluorescence microscopy. Unexpectedly, the hydrodynamic radius of linear DNA was markedly smaller than that of circular DNA. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：255 / 259

页数：5

共 15 条

[1] VISCOSITY SEDIMENTATION ET CETERA OF RING- AND STRAIGHT-CHAIN POLYMERS IN DILUTE SOLUTION [J].