Expression of Hel-N1 and Hel-N2 in small-cell lung carcinoma

被引：24

作者：

King, PH

Dropcho, EJ

机构：

[1] RICHARD L ROUDEBUSH VET AFFAIRS MED CTR,DEPT NEUROL,INDIANAPOLIS,IN 46202

[2] INDIANA UNIV,MED CTR,DEPT NEUROL,INDIANAPOLIS,IN

来源：

ANNALS OF NEUROLOGY | 1996年 / 39卷 / 05期

关键词：

D O I：

10.1002/ana.410390520

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Hel-N1 and HuD are neuron-specific RNA-binding proteins that are antigenic targets of anti-Hu antibodies. Although expression of Hu antigens is most commonly seen in small-cell lung carcinoma, their exact identity (e.g., Hel-N1, Hel-N2, HuD, and HuC) cannot be distinguished by immunological methods. Analysis of messenger RNA expression is needed for this distinction. Here we demonstrate that Hel-N1 and Hel-N2 are expressed in small-cell lung carcinoma using reverse transcription-polymerase chain reaction.

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页码：679 / 681

页数：3

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