Sexual mixing patterns in the spread of gonococcal and chlamydial infections

被引:199
作者
Aral, SO
Hughes, JP
Stoner, B
Whittington, W
Handsfield, HH
Anderson, RM
Holmes, KK
机构
[1] Ctr Dis Control & Prevent, Div STD Prevent, Natl Ctr HIV STD & TB Prevent, Atlanta, GA 30333 USA
[2] Univ Washington, Dept Med, Seattle, WA 98195 USA
[3] Univ Washington, Dept Biostat, Seattle, WA 98195 USA
[4] Univ Washington, Ctr AIDS & STD, Seattle, WA 98195 USA
[5] Seattle King Cty Dept Publ Hlth, Seattle, WA USA
[6] Washington Univ, Dept Med, St Louis, MO 63130 USA
[7] Washington Univ, Dept Anthropol, St Louis, MO 63130 USA
[8] Univ Oxford, Dept Zool, Oxford OX1 3PS, England
关键词
D O I
10.2105/AJPH.89.6.825
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objectives. This study sought to define, among sexually transmitted disease (STD) clinic attendees, (1) patterns of sex partner selection, (2) relative risks for gonococcal or chlamydial infection associated with each mixing pattern, and (3) selected links and potential and actual bridge populations. Methods. Mixing matrices were computed based on characteristics of the study participants and their partners. Risk of infection was determined in study participants with various types of partners, and odds ratios were used to estimate relative risk of infection for discordant vs concordant partnerships. Results. Partnerships discordant in terms of race/ethnicity, age, education, and number of partners were associated with significant risk for gonorrhea and chlamydial infection. In low-prevalence subpopulations, within-subpopulation mixing was associated with chlamydial infection, and direct links with high-prevalence subpopulations were associated with gonorrhea. Conclusions. Mixing patterns influence the risk of specific infections, and they should be included in risk assessments for individuals and in the design of screening, health education, and partner notification strategies for populations.
引用
收藏
页码:825 / 833
页数:9
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