Design and evaluation of a semantic approach for the homogeneous identification of events in eight patient databases: a contribution to the European EU-ADR project

被引：13

作者：

Avillach, Paul ^{[1
,2
]}

Joubert, Michel ^{[2
]}

Thiessard, Frantz ^{[1
]}

Trifiro, Gianluca ^{[3
]}

Dufour, Jean-Charles ^{[2
]}

Pariente, Antoine ^{[4
]}

Mougin, Fleur ^{[1
]}

Polimeni, Giovanni ^{[3
]}

Catania, Maria Antonietta ^{[3
]}

Giaquinto, Carlo ^{[5
]}

Mazzaglia, Giampiero ^{[6
]}

Fornari, Carla ^{[7
]}

Herings, Ron ^{[8
]}

Gini, Rosa ^{[9
]}

Hippisley-Cox, Julia ^{[10
]}

Molokhia, Mariam ^{[11
]}

Pedersen, Lars ^{[12
]}

Fourrier-Reglat, Annie ^{[4
]}

Sturkenboom, Miriam ^{[13
]}

Fieschi, Marius ^{[2
]}

机构：

[1] Uni Bordeaux 2, ISPED, LESIM, Bordeaux, France

[2] Uni Mediterranee, Fac Med, LERTIM, Marseille, France

[3] IRCCS Ctr Neurolesi Bonino Pulejo, Messina, Italy

[4] Uni Victor Segalen Bordeaux 2, INSERM, U 657, Bordeaux, France

[5] Pedianet Soc Serv Telemat SRL, Bordeaux, France

[6] Hlth Search Italian Coll Gen Practitioners, Bordeaux, France

[7] Univ Milano Bicocca, Ctr Publ Hlth, Milan, Italy

[8] PHARMO Cooperat UA, Amsterdam, Netherlands

[9] Reg Hlth Agcy Tuscany, Florence, Italy

[10] Uni Nottingham, Nottingham, England

[11] London Sch Hyg & Trop Med, London, England

[12] Aarhus Uni Hosp, Arhus Sygehus, Denmark

[13] Erasmus Uni, Med Ctr, IPCI Dept Med Informat, Rotterdam, Netherlands

来源：

MEDINFO 2010, PTS I AND II | 2010年 / 160卷

关键词：

Drug toxicity; Semantics; Medical records; Indexing; Information storage and retrieval; UMLS; MEDICAL LANGUAGE SYSTEM; TERMINOLOGY;

D O I：

10.3233/978-1-60750-588-4-1085

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

The overall objective of the EU-ADR project is the design, development, and validation of a computerised system that exploits data from electronic health records and biomedical databases for the early detection of adverse drug reactions. Eight different databases, containing health records of more than 30 million European citizens, are involved in the project. Unique queries cannot be performed across different databases because of their heterogeneity: Medical record and Claims databases, four different terminologies for coding diagnoses, and two languages for the information described in free text. The aim of our study was to provide database owners with a common basis for the construction of their queries. Using the UMLS, we provided a list of medical concepts, with their corresponding terms and codes in the four terminologies, which should be considered to retrieve the relevant information for the events of interest from the databases.

引用

页码：1085 / 1089

页数：5

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