Self-assembling urea-based peptidomimetics: A simple one-step synthesis and crystal structure of core beta-alanyl ureylene retro-bispeptides (MeO-A(aa)-[NH-CO-NH]-CH2-CH2-CO-NH-A(aa)-OMe; A(aa)=amino acid A)

被引：19

作者：

Ranganathan, D

Kurur, S

Madhusudanan, KP

Karle, IL

机构：

[1] CENT DRUG RES INST,LUCKNOW 226001,UTTAR PRADESH,INDIA

[2] USN,RES LAB,STRUCT MATTER LAB,WASHINGTON,DC 20375

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 26期

关键词：

D O I：

10.1016/S0040-4039(97)00960-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel family of urea-based peptidomimetics containing beta-alanyl unit at the core has been synthesized by a simple one-step procedure. Solid state structures of some representative examples have showm self-assembly into highly ordered extended hydrogen-bonded chains and ribbons with modest NLO activity. (C) 1997 Elsevier Science Ltd.

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页码：4659 / 4662

页数：4

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