Robustaquinones, novel anthraquinones from an elicited Cinchona robusta suspension culture

被引：36

作者：

Schripsema, J

Ramos-Valdivia, A

Verpoorte, R

机构：

[1] Univ Fed Rio de Janeiro, Nucleo Pesquisas Produtos Naturais, Ctr Ciencias Saude, BR-21941590 Rio De Janeiro, Brazil

[2] Leiden Univ, Div Pharmacognosy, Ctr Biopharmaceut Sci, Gorlaeus Labs, NL-2300 RA Leiden, Netherlands

[3] Inst Politecn Nacl, Ctr Invest & Estudios Avanzados, Dept Biotecnol, CINVESTAV, Mexico City 07000, DF, Mexico

来源：

PHYTOCHEMISTRY | 1999年 / 51卷 / 01期

关键词：

Cinchona robusta; Rubiaceae; anthraquinones; elicitation; biosynthesis;

D O I：

10.1016/S0031-9422(98)00470-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A suspension culture of Cinchona robusta which under normal culture conditions does not produce anthraquinones, produces a range of these anthraquinones after elicitation. Eight new anthraquinones were identified, robustaquinones A-H, in addition to two known anthraquinones, 1,3,8-trihydroxy-2-methoxyanthraquinone and copareolatin 6-methyl ether. Their oxygenation pattern, characterized by a 6,7-disubstitution in the A-ring, is rare and raises questions about their biogenetic origin. They might be derived from phenylpropanoids and not from o-succinylbenzoic acid. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：55 / 60

页数：6

共 18 条

[1] NATURALLY OCCURRING QUINONES .15. BIOGENESIS O ANTHRAQUINONES IN RUBIA TINCTORUM L (MADDER) [J].