Block the FAS, lose the fat

被引：70

作者：

Mobbs, CV ^{[1
]}

Makimura, H ^{[1
]}

机构：

[1] Mt Sinai Sch Med, Neurobiol & Aging Labs, New York, NY 10029 USA

来源：

NATURE MEDICINE | 2002年 / 8卷 / 04期

关键词：

D O I：

10.1038/nm0402-335

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A small-molecular-weight drug originally developed to treat cancer produces sustained reduction in body weight in obese mice by a novel hypothalamic mechanism. The findings suggest new targets for the development of anti-obesity drugs.

引用

页码：335 / 336

页数：2

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