Primary progressive freezing gait: A syndrome with many causes

被引：66

作者：

Factor, SA

Higgins, DS

Qian, J

机构：

[1] Emory Univ, Sch Med, Dept Neurol, Wesley Woods Hlth Ctr, Atlanta, GA 30329 USA

[2] Albany Med Ctr, Parkinsons Dis & Movement Disorders Ctr, Albany, NY USA

[3] Albany Med Ctr, Dept Pathol, Albany, NY USA

来源：

NEUROLOGY | 2006年 / 66卷 / 03期

关键词：

D O I：

10.1212/01.wnl.0000196469.52995.ab

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Primary progressive freezing gait (PPFG) is characterized by early gait freezing and a stereotyped progression. Of nine patients followed up for 6 to 16 years, two were diagnosed pathologically: pallidonigroluysian degeneration (PNLD) and diffuse Lewy body disease. Four others evolved clinically into progressive supranuclear palsy and corticobasal degeneration. PPFG is not a distinct disorder but a syndrome with diverse causes. Long-term follow-up (>= 10 years) and postmortem are required for accurate diagnosis. PNLD may be the primary form of disease.

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页码：411 / 414

页数：4

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