A novel method for stereoselective synthesis of beta-trifluoromethylated homoallylic alcohols in water

被引：47

作者：

Loh, TP

Li, XR

机构：

[1] Department of Chemistry, National University of Singapore, Singapore 119260

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(96)02434-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The indium-mediated allylation reaction of aldehydes with 1,1,1-trifluoro-4-bromo-2-butene in water afforded an important trifluoromethylated building block beta-trifluoromethylated homoallylic alcohol with high yield and excellent diastereoselectivity. (C) 1997, Elsevier Science Ltd.

引用

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页码：869 / 872

页数：4

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