Cryptogenic cirrhosis and NAFLD: Are they related?

被引：61

作者：

Maheshwari, A ^{[1
]}

Thuluvath, PJ ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Baltimore, MD USA

来源：

AMERICAN JOURNAL OF GASTROENTEROLOGY | 2006年 / 101卷 / 03期

关键词：

D O I：

10.1111/j.1572-0241.2006.00478.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Cryptogenic cirrhosis (CC), literally meaning cirrhosis of obscure or unknown origin, is a diagnosis of exclusion. The circumstantial evidence indicates that nonalcoholic fatty liver disease (NAFLD) is perhaps one of the important causes of CC. There is also evidence, especially from the European literature, that some patients with CC may have undiagnosed or burnt-out autoimmune hepatitis (AIH). Other rare causes may include "unknown" viral (non-A, non-B, non-C) hepatitis, and occult alcoholism. In this review, we examine the role of NAFLD and other causes in the pathogenesis of CC, and the impact of obesity on patients with chronic liver disease.

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页码：664 / 668

页数：5

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