Heart failure in elderly patients: distinctive features and unresolved issues

被引：136

作者：

Lazzarini, Valentina ^{[1
,2
]}

Mentz, Robert J. ^{[1
,3
]}

Fiuzat, Mona ^{[1
,3
]}

Metra, Marco ^{[2
]}

O'Connor, Christopher M. ^{[1
,3
]}

机构：

[1] Duke Univ, Med Ctr, Duke Clin Res Inst, Durham, NC USA

[2] Univ Brescia, Dept Med Specialties Radiol Sci & Publ Hlth, I-25123 Brescia, Italy

[3] Duke Univ, Med Ctr, Dept Med, Div Cardiol, Durham, NC 27710 USA

来源：

EUROPEAN JOURNAL OF HEART FAILURE | 2013年 / 15卷 / 07期

关键词：

Heart failure; Heart failure with preserved ejection fraction; Elderly; Outcomes; Therapy; OLDER PATIENTS; CLINICAL-OUTCOMES; EJECTION FRACTION; EUROPEAN-SOCIETY; RANDOMIZED-TRIAL; MORTALITY; CARE; AGE; PREDICTORS; DIAGNOSIS;

D O I：

10.1093/eurjhf/hft028

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The prevalence of heart failure (HF) increases with age. While clinical trials suggest that contemporary evidence-based HF therapies have reduced morbidity and mortality, these trials largely excluded the elderly. Questions remain regarding the clinical characteristics of elderly HF patients and the impact of contemporary therapies on their outcomes. This review presents the epidemiology of HF in the elderly and summarizes the data on the pathophysiology of the ageing heart. The clinical characteristics, treatment patterns, and outcomes of elderly HF patients are explored. Finally, the main gaps regarding HF therapies in the elderly and the opportunities for future trials are highlighted.

引用

页码：717 / 723

页数：7

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